Korean J Dermatol.  2001 Jan;39(1):96-98.

A Case of Tuberculosis Verrucosa Cutis

• Cha JH
• Jang HS
• Oh CK
• Kwon KS

Abstract

We report a case of tuberculosis verrucosa cutis in a 64-year-old male patient, who had multiple verrucous plaques on his right hand for twenty years. His past history revealed a previous history of injury on his lesion site. Histologic features consisted of hyperkeratosis, acanthosis in the epidermis with inflammatory infiltrate and tuberculoid granuloma in the dermis. It was suspected that the patient had tuberculosis verrucosa cutis, but no bacilli was found in the lesion in the AFB stain. Then we performed PCR, which showed a positive result. We started antituberculosis medication, and the lesions cleared up after 6 months of treatment with isoniazid, rifampicin, pyrazinamide, and ethambutol. The lesions were later confirmed to be tuberculosis by the AFB culture. We suggest that early diagnosis of tuberculosis verrucosa cutis can be made by using PCR.

Keyword

Tuberculosis verrucosa cutis; PCR

MeSH Terms

Dermis
Early Diagnosis
Epidermis
Ethambutol
Granuloma
Hand
Humans
Isoniazid
Male
Middle Aged
Polymerase Chain Reaction
Pyrazinamide
Rifampin
Tuberculosis*
Ethambutol
Isoniazid
Pyrazinamide
Rifampin