Korean J Asthma Allergy Clin Immunol.  2004 Sep;24(3):337-339.

A Case of Acute Respiratory Failure Caused by Non-ionic Radiocontrast Media in a Bronchial Asthma Patient

Abstract

Anaphylaxis to radiocontrast media is occurred immediately after exposure and this may be life threatening. Persons with a history of allergy and asthma, female and beta-blocker user are at increased risk for an anaphylactoid reaction to radiocontrast media. Here we describe a case of asthma patient who experienced acute respiratory failure occurring in anaphylaxis to nonionic radiocontrast media. A 51-year-old man presented with acute respiratory failure following the administration of nonionic contrast media (iopromide) for a chest computed tomography. An arterial blood gas analysis during this reaction revealed pH 7.123, PCO2 60.5 mmHg, PaO2 53.9 mmHg, and SO2 76.3%. He was successfully resuscitated with prompt intubation and medical therapy including subcutaneous injection of epinephrine and beta-agonist, intravenous administration of steroid, and aminophylline. Three hours later he fully recovered to be extubated. This case suggests that medical emergency backup is needed to ensure resuscitation in an anaphylaxis to a radiocontrast media.


MeSH Terms

Administration, Intravenous
Aminophylline
Anaphylaxis
Asthma*
Blood Gas Analysis
Contrast Media*
Emergencies
Epinephrine
Female
Humans
Hydrogen-Ion Concentration
Hypersensitivity
Injections, Subcutaneous
Intubation
Middle Aged
Respiratory Insufficiency*
Resuscitation
Thorax
Aminophylline
Contrast Media
Epinephrine
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