Korean J Anesthesiol.  1997 Dec;33(6):1220-1224. 10.4097/kjae.1997.33.6.1220.

Postoperative Severe Hemorrhage Due to Disseminated Intravascular Coagulation: A case report

Abstract

Disseminated intravascular coagulation (DIC) is a pathological syndrome in which activation of coagulation cascade leads to fibrin clot formation, consumption of platelets and coagulation factors, and secondary fibrinolysis. We report a case of severe postoperative hemorrhagic diathesis due to DIC. A 59-year-old man was scheduled for reduction of tibia fracture and anatrophic nephrolithotomy of staghorn calculi. On the fifth postoperative day, second operation was performed for nephrectomy due to perirenal hematoma. Two days later, third operation was performed for hemostasis because of the continuous bleeding. Coagulation tests showed positive DIC profiles of thrombocytopenia, hypofibrinogenemia, increased fibrin degradation products, and prolonged prothrombin time and thrombin time. The patient recovered uneventfully and discharged on the 59th postoperative day.

Keyword

Blood, disseminated intravascular coagulation; Complications, postoperative; Hemorrhage

MeSH Terms

Blood Coagulation Factors
Calculi
Dacarbazine
Disseminated Intravascular Coagulation*
Fibrin
Fibrin Fibrinogen Degradation Products
Fibrinolysis
Hematoma
Hemorrhage*
Hemorrhagic Disorders
Hemostasis
Humans
Middle Aged
Nephrectomy
Postoperative Complications
Prothrombin Time
Thrombin Time
Thrombocytopenia
Tibia
Blood Coagulation Factors
Dacarbazine
Fibrin
Fibrin Fibrinogen Degradation Products
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