J Korean Acad Fam Med.  1997 Jan;18(1):22-28.

Prevalence of Helicobacter Pylori Infection in Upper Gastrointestinal Diseases

• Kwag IS
• Song GS
• Jang TJ
• Jung MK

Abstract

BACKGROUND: The Helicobacter pylori(H. pylori) is associated with chronic gastritis and is now recognized to be the main factor in the pathogenesis of peptic ulcer disease. The eradication treatment of H. pylori significantly lowers ulcer relapse rate, which is accompanied by important histological change. We evaluated the prevalence of H. pylori infection in upper gastrointestinal diseases.
METHODS
Total 491 patients(274 with chronic gastritis, 134 with gastric ulcer, 57 with duodenal ulcer, and 26 with gastroduodenal ulcer) were tested for H. pylori infection by the CLO test, hematoxylin-eosin stain and Giemsa stain.
RESULTS
The prevalence of H. pylori infection was 74.0% in male and 58.6% in female. The prevalence of H. pylori infection was 73.2% in 30-59 year-old group and 60.2% in older age group. The sex and age adjusted prevalence of H. pylori infection was 64.7% in chronic gastritis, 69.4% in gastric ulcer, 84.5% in duodenal ulcer and 87.8% in gastroduodenal ulcer.
CONCLUSIONS
The prevalence of H. pylori infection of upper gastrointestinal diseases is significantly higher in male, 30-59 year-old group, peptic ulcer and duodenal ulcer than in female, older age group(over 60), chronic gastritis and gastric ulcer, respectively.

MeSH Terms

Azure Stains
Duodenal Ulcer
Female
Gastritis
Gastrointestinal Diseases*
Helicobacter pylori*
Helicobacter*
Humans
Male
Peptic Ulcer
Prevalence*
Recurrence
Stomach Ulcer
Ulcer
Azure Stains