Korean J Urol.  2006 Jan;47(1):108-110. 10.4111/kju.2006.47.1.108.

Contralateral Testicular Single Metastasis from Renal Cell Carcinoma

• Lee DH
• Yang KM
• Lee KW
• Oh YT
• Hong SJ

• KMID: 2294226
• DOI: http://doi.org/10.4111/kju.2006.47.1.108

Abstract

Approximately one-third of all patients with renal cell carcinoma have metastases at the time of diagnosis. Metastasis of renal cell carcinoma (RCC) to the testis is a rare finding. The cases of testicular metastasis from renal cell carcinoma that have been reported in the literature are predominantly ipsilateral, and they are invariably found on the left side through the retrograde venous spread along the gonadal artery. We experienced a case of contralateral testicular metastasis from a right side renal cell carcinoma, so we discuss the clinical feature and pathophysiology of this case with a review of the related literature.

Keyword

Renal cell carcinoma; Testis; Metastasis

MeSH Terms

Arteries
Carcinoma, Renal Cell*
Diagnosis
Gonads
Humans
Neoplasm Metastasis*
Testis

Figure

• 

  Fig. 1 Inhomogeneous right side renal tumor.

• 

  Fig. 2 Heterogeneous echogenic mass with tortuous and dilated blood vessels, and fluid collection around the mass is also seen.

• 

  Fig. 3 The well circumscribed variegated solid mass measuring 5×3.5cm.

• 

  Fig. 4 (A) Renal cell carcinoma (RCC) of the clear cell type in the right kidney. (B) The same histologic features are seen in the left testis.

Reference

1. Pagano S, Franzoso F, Ruggeri P. Renal cell carcinoma metastases. Scand J Urol Nephrol. 1996. 30:165–172.

2. Datta MW, Ulbright TM, Young RH. Renal cell carcinoma metastatic to the testis and its adnexa: a report of five cases including three that accounted for initial clinical presentation. Int J Surg Pathol. 2001. 9:49–56.

3. Pienkos EJ, Jablokow VR. Secondary testicular tumors. Cancer. 1972. 30:481–485.

4. Saitoh H. Distant metastasis of renal adenocarcinoma. Cancer. 1981. 48:1487–1491.

5. Tolia BM, Whitmore WF Jr. Solitary metastasis from renal cell carcinoma. J Urol. 1975. 114:836–838.

6. Blefari F, Risi O, Pino P. Secondary tumors of testis: two rare cases and review of the literature. Urol Int. 1992. 48:469–470.

7. Lauro S, Lanzetta G, Bria E, Trasatti L, Costarelli L, Vecchione A. Contralateral solitary testis metastasis antedating renal cell carcinoma: a case-report and review. Anticancer Res. 1998. 18:4683–4684.

8. Nabi G, Gania MA, Sharma MC. Solitary delayed contralateral testicular metastasis from renal cell carcinoma. Indian J Pathol Microbiol. 2001. 44:487–488.

9. Middleton RG. Surgery for metastatic renal cell carcinoma. J Urol. 1967. 97:973–977.