Korean J Urol.  2004 Feb;45(2):181-184.

Primitive Neuroectodermal Tumor of the Kidney

Affiliations
  • 1Department of Urology, Hanyang University College of Medicine, Seoul, Korea.
  • 2Department of Pathology, Hanyang University College of Medicine, Seoul, Korea.

Abstract

Primitive neuroectodermal tumor (PNET), also referred to as extraskeletal Ewing's sarcoma, is a highly aggressive tumor, and it is seen typically in the soft tissues of the chest wall and paraspinal region but rarely arises in the kidney. A 27-year-old woman was presented with a left renal mass and underwent a radical nephrectomy. The pathological diagnosis was a primitive neuroectodermal tumor. Microscopically, there were sheets and lobules of cells with round to oval nuclei and coarse chromatin, as well as a Homer Wright rosette formation. Immunohistochemical analysis showed strongly positive staining of CD99 and negative staining of other neuroendocrine markers, such as synaptophysin and chromogranin.

Keyword

Primitive neuroectodermal tumor (PNET); Immunotherapy; Kidney

MeSH Terms

Adult
Chromatin
Diagnosis
Female
Humans
Immunotherapy
Kidney*
Negative Staining
Nephrectomy
Neuroectodermal Tumors, Primitive*
Rosette Formation
Sarcoma, Ewing
Synaptophysin
Thoracic Wall
Chromatin
Synaptophysin
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