J Korean Acad Child Adolesc Psychiatry.  2010 Feb;21(1):3-10.

Major Lessons from the MTA in Treatment of Attention-Deficit Hyperactivity Disorder

• Hwang JW

Abstract

OBJECTIVES
The current review aimed to describe the major findings of the NIMH Collaborative Multisite Multimodal Treatment Study of Children with Attention-Deficit Hyperactivity Disorder (MTA) with regard to the treatment of children with attention-deficit hyperactivity disorder (ADHD).
METHODS
We performed a general review of the literature regarding the efficacy of the MTA's proposed treatments.
RESULTS
There is a large and still increasing body of evidence regarding the MTA's treatment outcomes. We present and discuss details of the findings at each follow-up point.
CONCLUSION
Currently, findings regarding the MTA's treatments suggest children with combined-type ADHD exhibit significant impairment in adolescence, despite their initial symptom improvement. Further studies, using innovative treatment approaches and targeting specific areas of adolescent impairment, are needed in order to enhance ADHD treatment outcomes.

Keyword

Attention-Deficit Hyperactivity Disorder; MTA; Medication Treatment; Behavioral Treatment

MeSH Terms

Adolescent
Child
Combined Modality Therapy
Follow-Up Studies
Glutamates
Guanine
Humans
National Institute of Mental Health (U.S.)
Pemetrexed
Glutamates
Guanine