Korean J Thorac Cardiovasc Surg.
2003 Aug;36(8):614-618.
Multimodal Treatment of Pleuropulmonary Blastoma: Two case report
- Affiliations
-
- 1Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea. jkim@smc.samsung.co.kr
- 2Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine
- 3Department of Pediatric Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine
Abstract
- Pleuropulmonary blastoma (PPB) is a rare intrathoracic neoplasm, found solely in childhood. The usual symptoms are dyspnea, chest discomfort, recurrent respiratory infections, fever, dry cough, and chest pain. The progress of PPB is usually aggressive and its progress is generally poor. Lymphatic spread to the hilar and mediastinal nodes can occur. Distant metastasis is found in brain, bones, and intra-abdominal organs. Surgical resection is the treatment of choice. When the disease is too extensive for surgical resection, neoadjuvant chemotherapy can be used. We report 2 cases of pleuropulmonary blastoma in children successfully treated with multimodal therapy.
