Korean J Sports Med.  2012 Jun;30(1):55-64. 10.5763/kjsm.2012.30.1.55.

Association of IGF-I Gene Polymorphism with Blood Concentration of IGF-I, Body Composition, Bone Age and Response to Combined Exercise Program in Teen-Aged Children

Affiliations
  • 1Department of Physical Education, Keimyung University, Daegu, Korea. kjk744@kmu.ac.kr

Abstract

Association of insulin like growth factor (IGF)-I gene polymorphism with blood concentration of IGF-I, body composition, bone age and response to combined exercise program in teen-aged children. The purpose
of this study was to determine whether there are the differences of blood concentration of IGF-I, body composition, bone age and response to combined exercise program according to IGF-I gene polymorphism in Korean teen-aged children. Subjects were recruited by 143 teen-aged children (male: 78, female: 65) from elementary school. Twelve weeks exercise program was consisted of resistance training and aerobic exercise. For the comparison of items and responses to combined exercise program according to IGF-I gene polymorphism, blood concentration of IGF-I, skinfold thickness, body circumferences, and growth markers were measured at baseline and after intervention. Body weight, %fat, BMI, skinfold thickness, circumferences, blood concentration of IGF-I, and bone age showed no significant differences following to IGF-I gene polymorphism. Although body composition and blood concentration of IGF-I showed a positive change after 12 week exercise training, 12 week exercise-mediated changes of body composition and blood concentration of IGF-I showed no significant differences following to IGF-I gene polymorphism. In conclusion, IGF-I gene polymorphism no contributed to the differences of body composition, blood concentration of IGF-I, and 12 week exercise-mediated these changes in teen-aged children.

Keyword

IGF-I gene polymorphism; Children; Growth; Exercise; Body composition
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