Korean J Psychopharmacol.  1997 Apr;8(1):142-147.

Plasma Homovanillic Acid Level in Posttraumatic Stress Disorder

Affiliations
  • 1Department of Neuropsychiatry, Korea Veternas Hospital, Seoul, Korea.
  • 2Department of Clinical Pathology, Korea Veterans Hospital, Seoul, Korea.

Abstract

This research was performed to investigate whether or not the psychobiology of posttraumatic stress disorder is related to dopamine systems. Plasma homovanillic acid levels were measured in 16 male patients with posttraumatic stress disorder and in 16 nonpsychiatric normal males. Posttraumatic stress disorder was diagnosed using the DSM-IV. Plasma homovanillic acid levels were significantly higher in patients with posttraumatic stress disorder than in normal control subjects(p<0.05). The findings of this study suggest that hyperactivity of dopamine systems may be related to the psychobiology of posttraumatic stress disorder.

Keyword

Posttraumatic stress disorder; Plasma homovanillic acid

MeSH Terms

Diagnostic and Statistical Manual of Mental Disorders
Dopamine
Homovanillic Acid*
Humans
Male
Plasma*
Stress Disorders, Post-Traumatic*
Dopamine
Homovanillic Acid
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