J Asthma Allergy Clin Immunol.  2002 Dec;22(4):742-746.

A case of eosinophilic panniculitis diagnosed in the lower extremity skin lesions with tenderness

• Lee HS
• Lee KC
• Oh JW
• Kim NJ
• Nam SY
• Kim HS
• Lee HR
• Jeong JW
• Kim WK

Abstract

Eosinophilic panniculitis is characterized by prominent infiltration of eosinophils in the subcutaneous fat. Clinically it may be considered as a reactive process because most patients have an associated systemic condition. We report a case of tender subcutaneous nodules and plaques with erythema on the lower legs in a 30-year-old man with blood eosinophilia. The histologic features were characterized by massive eosinophilic infiltration in the septae and lobule in the parenchymal area of subcutaneous tissues. Despite exhaustive investigation, no obvious trigger of the panniculitis could be identified. The cutaneous lesions regressed and the eosinophil count became normal during the seven days course of treatment with intravenous corticosteroid. Another flare-up occurred about one month after treatment. The patient is presently being treated with prolonged use of alternate-day steroid without recurrence.

Keyword

Eosinophilic panniculitis

MeSH Terms

Adult
Eosinophilia
Eosinophils*
Erythema
Humans
Leg
Lower Extremity*
Panniculitis*
Recurrence
Skin*
Subcutaneous Fat
Subcutaneous Tissue