Gut Liver.
2010 Jun;4(2):274-277.
A Case of Isolated Invasive Aspergillus Colitis Presenting with Hematochezia in a Nonneutropenic Patient with Colon Cancer
- Affiliations
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- 1Department of Internal Medicine, Chung-Ang University Medical Center, Chung-Ang University College of Medicine, Seoul, Korea. drjwchung@cau.ac.kr
- 2Department of Pathology, Chung-Ang University Medical Center, Chung-Ang University College of Medicine, Seoul, Korea.
Abstract
- Gastrointestinal invasive aspergillosis is often reported as part of a disseminated infection, and rarely as an isolated organ infection. Isolated invasive Aspergillus colitis is very rare, being observed only in patients with hematological malignancy and neutropenia. We encountered an unusual case of isolated invasive Aspergillus colitis presenting with hematochezia in a nonneutropenic patient with colon cancer. Fungal hyphae with surrounding inflammatory cells and mucosal necrosis were observed during the histological examination of a biopsy sample obtained at endoscopy. This case indicates that isolated invasive Aspergillus colitis may develop in a variable context of immunosuppression.
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