Korean J Perinatol.  2015 Sep;26(3):183-189. 10.14734/kjp.2015.26.3.183.

Clinical Consideration of Surveillance Cultures for Out-born Neonates Transferred to Neonatal Intensive Care Unit

• Lee SH
• Cho SW
• Yu ST
• Oh YK

• KMID: 2281221
• DOI: http://doi.org/10.14734/kjp.2015.26.3.183

Abstract

PURPOSE
To identify trends in bacterial organisms and antimicrobial susceptibilities for transmission by outborn neonates, it is important to perform surveillance cultures. The aim of this study was to investigate major organisms and any other clinical factors through surveillance cultures of out-born neonates who transferred to neonatal intensive care units (NICU).
METHODS
This study is a retrospective collected data among 189 out-born neonates admitted to NICU from Mar. 2012, to Feb. 2014. Surveillance cultures were obtained routinely from both nasal and axillary region and inoculated CHROM agar(TM) MRSA immediately. Bacterial culture identification and antibiotic susceptibility were carried out using Vitek II ID-GPI card.
RESULTS
The most prevalent organisms isolated from the nasal surveillance cultures were methicillin-resistant Staphylococcus aureus (MRSA) and coagulase negative Staphylococcus (CoNS) (each 17 cases vs. 11 cases); both vancomycin and rifampin were susceptible. Only 1 case of S. epidermidis has same result in blood and surveillance culture. Demographic, clinical and healthcare related parameters according to surveillance culture results were compared, but no obvious association was apparent on above parameters. Nevertheless, positive surveillance culture group showed lower birth weight and longer duration until transferred to NICU.
CONCLUSION
In our surveillance culture study showed that MRSA and CoNS were the most common organisms in out-born neonates; both were penicillin- and oxacillin-resistant on antibiotic susceptibility testing. Although there is no statistical meaning, positive surveillance culture group showed relatively lower birth weight and longer duration from birth to NICU arrival. These findings were contributed to obtain a reliable policy of the transmission in NICU.

Keyword

Surveillance; Neonatal intensive care units; Methicillin-resistant Staphylococcus aureus

MeSH Terms

Birth Weight
Coagulase
Delivery of Health Care
Humans
Infant, Newborn*
Intensive Care Units, Neonatal
Intensive Care, Neonatal*
Methicillin-Resistant Staphylococcus aureus
Parturition
Retrospective Studies
Rifampin
Staphylococcus
Vancomycin
Coagulase
Rifampin
Vancomycin

Figure

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  Fig. 1. Regional distribution of local clinics which transferred neonates.

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  Fig. 2. Antibiotics sensitivity result of surveillance culture organisms (MRSA, CoNS). Abbreviations: MRSA, methicillin-resistant Staphylococcus aureus; CoNS, Coagulase negative Staphylococcus; TMP/SMX, Trimethoprim-sulphamethoxazole; S, sensitivity; I, intermediate; R, resistance.

Reference

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