Korean J Pediatr.
2009 Oct;52(10):1175-1180. 10.3345/kjp.2009.52.10.1175.
A case of persistent pulmonary hypertension of the newborn: Treatment with inhaled iloprost
- Affiliations
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- 1Department of Pediatrics, School of Medicine, Catholic University of Daegu, Daegu, Korea. grapfarm@hanmail.net
- KMID: 2281064
- DOI: http://doi.org/10.3345/kjp.2009.52.10.1175
Abstract
- We report a case of a full-term neonate with persistent pulmonary hypertension who developed asphyxia after birth and was treated with iloprost. The neonate had persistent hypoxia and did not respond to supportive treatment. Because inhaled nitric oxide (iNO) was not available in our hospital, inhaled iloprost was administered via an endotracheal tube. This resulted in an immediate elevation of oxygen saturation. Echocardiography revealed the conversion of the right-to-left ductal shunt to the left-to-right one and a decrease of the right ventricular pressure. The use of inhaled iloprost did not cause any significant side effects. Here, we describe our experience where iloprost was used in a neonate with persistent pulmonary hypertension because the standard therapy with inhaled nitric oxide was not available.
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