Korean J Pediatr.  2009 Oct;52(10):1175-1180. 10.3345/kjp.2009.52.10.1175.

A case of persistent pulmonary hypertension of the newborn: Treatment with inhaled iloprost

Affiliations
  • 1Department of Pediatrics, School of Medicine, Catholic University of Daegu, Daegu, Korea. grapfarm@hanmail.net

Abstract

We report a case of a full-term neonate with persistent pulmonary hypertension who developed asphyxia after birth and was treated with iloprost. The neonate had persistent hypoxia and did not respond to supportive treatment. Because inhaled nitric oxide (iNO) was not available in our hospital, inhaled iloprost was administered via an endotracheal tube. This resulted in an immediate elevation of oxygen saturation. Echocardiography revealed the conversion of the right-to-left ductal shunt to the left-to-right one and a decrease of the right ventricular pressure. The use of inhaled iloprost did not cause any significant side effects. Here, we describe our experience where iloprost was used in a neonate with persistent pulmonary hypertension because the standard therapy with inhaled nitric oxide was not available.

Keyword

Persistent fetal circulation syndrome; Iloprost

MeSH Terms

Anoxia
Asphyxia
Echocardiography
Female
Humans
Hypertension, Pulmonary
Iloprost
Infant, Newborn
Nitric Oxide
Oxygen
Parturition
Persistent Fetal Circulation Syndrome
Ventricular Pressure
Iloprost
Nitric Oxide
Oxygen
Full Text Links
  • KJP
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr