Korean J Perinatol.  2014 Sep;25(3):153-158. 10.14734/kjp.2014.25.3.153.

The Most Important Factors for Retinopathy of Prematurity in Preterm Infants

• Choi JY
• Han YI
• Kim JH
• Kim ES
• Jeon J

• KMID: 2280988
• DOI: http://doi.org/10.14734/kjp.2014.25.3.153

Abstract

PURPOSE
There are many known risk factors for a retinopathy of prematurity (ROP). We analyzed the most important risk factors and predictors of ROP among them.
METHODS
We retrospectively reviewed the medical records of all premature infants admitted to the neonatal intensive care unit (NICU), between January 2010 and December 2012 at Gangnam CHA Medical Center, Seoul. . All infants (n=185) were hospitalized for more than 28 days, received eye examination for ROP and showed one of the following criteria: birth weight (BW) below 1,500 g, gestational age (GA) below 32 weeks, or oxygen treatment (> or =40% oxygen for more than 3 days). We divided the infants into the Non-ROP group (n=162) and the ROP group (n=23, more than stage 1) and analyzed group comparisons, risk factors and the importance of each factor of ROP by SPSS 13.0.
RESULTS
Risk factors were duration of oxygen uses [Odds ratio (OR): 1.064, 95% confidence interval (CI): 1.007-1.125, P=0.028] and intravenous (IV) steroid (OR: 1.234, 95% CI: 1.000-1.523, P=0.049) by multi-factor adjustment. The most important factor was oxygenation duration. The following factors were time to full enteral feedings, and IV steroid duration.
CONCLUSION
The incidence of ROP will be decreased if we can reduce the length of oxygen uses, IV steroid use and advance the full feeding achievement.

Keyword

Retinopathy of prematurity; Risk factor; Oxygen; Enteral feeding; Steroid

MeSH Terms

Birth Weight
Enteral Nutrition
Gestational Age
Humans
Incidence
Infant
Infant, Newborn
Infant, Premature*
Intensive Care, Neonatal
Medical Records
Oxygen
Retinopathy of Prematurity*
Retrospective Studies
Risk Factors
Seoul
Oxygen

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