Clin Psychopharmacol Neurosci.  2014 Aug;12(2):160-162.

Combined Clozapine and Electroconvulsive Therapy in a Japanese Schizophrenia Patient: A Case Report

  • 1Department of Neuropsychiatry, Ehime University Graduate School of Medicine, Shitsukawa, Japan.
  • 2Department of Postgraduate Clinical Training Center, Ehime University Hospital, Shitsukawa, Japan.


Clozapine is well-known for successful use in schizophrenic patients treatment resistant to other antipsychotics. However, even with clozapine, 25% of schizophrenic patients are not in remission. Recently, as adjunctive treatment with clozapine, electroconvulsive therapy has been reported to be an effective and safe adjunctive treatment. We report a Japanese schizophrenic woman who was not in remission with clozapine alone but with both clozapine and electroconvulsive therapy.


Schizophrenia; Clozapine; Electroconvulsive therapy; Lithium
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