Korean J Pediatr.  2006 Jun;49(6):691-695. 10.3345/kjp.2006.49.6.691.

A case of recurrent hepatoblastoma: lung, heart and brain metastasis

Affiliations
  • 1Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea. kimhs@dsmc.or.kr
  • 2Department of Radiology, Keimyung University School of Medicine, Daegu, Korea.

Abstract

Hepatoblastoma is a hepatic tumor predominantly occurring in children. The usual site of metastasis is the lung. There are only several reports worldwide on the distant metastasis of hepatoblastoma to the central nervous system in children. Only one reported case showed survival of a patient after multiple resections of a recurrent brain lesion. Involvement of the cardiovascular system has been reported in the medical literature. Lesions almost always involve the right-side of the heart. We report a case of recurrent hepatoblastoma at multiple sites, including brain, left atrium of the heart and lung in a 6-year-old girl who was partially treated in the past at the age of 1.5 years; the patient had been event-free for four and a half years.

Keyword

Hepatoblastoma; Metastasis; Left atrium; Brain

MeSH Terms

Brain*
Cardiovascular System
Central Nervous System
Child
Female
Heart Atria
Heart*
Hepatoblastoma*
Humans
Lung*
Neoplasm Metastasis*
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