Clin Nutr Res.  2014 Jan;3(1):56-63. 10.7762/cnr.2014.3.1.56.

Comparison of Nutrient Intake and Diet Quality Between Hyperuricemia Subjects and Controls in Korea

Affiliations
  • 1Department of Clinical Nutrition, National Cancer Center, Goyang 410-769, South Korea. gawie@ncc.re.kr
  • 2Division of Cancer Epidemiology & Prevention, Research Institute, National Cancer Center, Goyang 410-769, South Korea.
  • 3Center for Cancer Prevention and Detection, National Cancer Center, Goyang 410-769, South Korea.

Abstract

Hyperuricemia is associated with metabolic syndrome as well as gout, and the prevalence of hyperuricemia is increasing in Korea. This study aimed to compare the nutrient intake and diet quality between hyperuricemia subjects and controls. Of the 28,589 people who participated in a health examination between 2008 and 2011, 9,010 subjects were selected whose 3-day food records were available. Clinical and laboratory data were collected from electronic medical records. Diet quality was evaluated using the food habit score (FHS), nutrient adequacy ratio (NAR), and mean adequacy ratio (MAR). The prevalence of hyperuricemia was 13.8% (27.1%, men; 5.2%, women). Body mass index, waist circumference, triglycerides, total cholesterol, and low-density lipoprotein cholesterol were significantly higher (p < 0.0001), while high-density cholesterol (p < 0.001) was significantly lower in the hyperuricemia subjects than in the controls. The hyperuricemia subjects had a lower intake of vitamin A (p < 0.004), vitamin C, folate, fiber, and calcium than the controls (p < 0.0001). Intake of vegetables and dairy products was significantly lower, whereas alcohol intake was significantly higher in the hyperuricemia subjects than in the controls ( p < 0.0001). The FHS (p < 0.0001), MAR (p < 0.0001), and NARs for vitamin A (p = 0.01), vitamin B2, vitamin C, folate, and calcium (p < 0.0001) were significantly lower in the hyperuricemia subjects than in the controls. In conclusion, the hyperuricemia subjects reported poorer diet quality than the controls, including higher alcohol intake and lower vegetable and dairy product intake.

Keyword

Hyperuricemia; Uric acid; Diet records; Nutritive Value; Food Habits

MeSH Terms

Ascorbic Acid
Body Mass Index
Calcium
Cholesterol
Dairy Products
Diet Records
Diet*
Electronic Health Records
Folic Acid
Food Habits
Gout
Humans
Hyperuricemia*
Korea*
Lipoproteins
Male
Nutritive Value
Prevalence
Riboflavin
Triglycerides
Uric Acid
Vegetables
Vitamin A
Waist Circumference
Ascorbic Acid
Calcium
Cholesterol
Folic Acid
Lipoproteins
Riboflavin
Triglycerides
Uric Acid
Vitamin A

Figure

  • Figure 1 Inclusion and exclusion criteria for the study subjects. *Visitors for health examination survey from January 1, 2008 to December 31, 2011; †Hyperuricemia was defined as serum uric acid concentration ≥7 mg/dL in men, and ≥6 mg/dL in women [16].


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