Korean J Pathol.  2006 Apr;40(2):151-155.

Follicular Lymphoma with Monoclonal Plasma Cell Differentiation: A Case Report

Affiliations
  • 1Department of Pathology, Korea University Medical College, Seoul, Korea. iskim@korea.ac.kr

Abstract

We present a case of recurrent follicular lymphoma with an extensive plasma cell component involving infra-auricular lymph nodes in a 64 year-old woman. Immunohistochemical staining showed a strongly positive reaction of the follicles with CD20, bcl-2, bcl-6, CD10 and CD21 on the first biopsy specimen. The intrafollicular and interfollicular plasma cells showed monoclonality for IgG heavy chain and lambda light chain. The histological and immunohistochemical findings in the recurrent tumor were identical with those of the original. Discussion is focused on the importance of the differential diagnosis between reactive lymphoid hyperplasia and other lymphomas having plasmacytic differentiation.

Keyword

Inflammatory myofibroblastic tumor; Inflammatory pseudotumor; ALK; Stomach

MeSH Terms

Biopsy
Diagnosis, Differential
Female
Granuloma, Plasma Cell
Humans
Immunoglobulin G
Lymph Nodes
Lymphoma
Lymphoma, Follicular*
Middle Aged
Plasma Cells*
Plasma*
Pseudolymphoma
Stomach
Immunoglobulin G
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