Korean J Pathol.  2010 Aug;44(4):420-425.

Solitary Fibrous Tumor of the Kidney: A Report of Two Cases with Review of Literature

• Kim SA
• Hwang JE
• Ro JY
• Cho KJ
• Song C
• Kim MJ

Abstract

Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm usually occurring in the pleura. Kidney is one of the rarest sites for SFT. We report here on two cases of renal SFT found in 30-year-old and 33-year-old men with review of the literatures. Both cases manifested as well-enhanced solid masses in kidney and radical nephrectomies were done. The tumors consisted of bland-looking spindle cells arranged in short, ill-defined fascicles and storiform pattern with characteristic hemangiopericytoma-like blood vessels. The tumor cells were strongly positive for CD34 and CD99, focally positive for bcl-2, and negative for cytokeratin and human melanoma black-45 on immunohistochemical stainings. Possibility of SFT should be considered in the differential diagnosis of a renal mass which consists of benign-looking spindle cells and hemangiopericytomatous blood vessels. Immunohistochemical staining for CD34 is essential to confirm the renal solitary fibrous tumor.

Keyword

Solitary fibrous tumor; Kidney; Immunohistochemistry

MeSH Terms

Adult
Blood Vessels
Diagnosis, Differential
Humans
Immunohistochemistry
Keratins
Kidney
Male
Melanoma
Nephrectomy
Pleura
Solitary Fibrous Tumors
Keratins