Korean J Pathol.  2010 Oct;44(5):543-546.

Jugulotympanic Paraganglioma, Mimicking a Vascular Tumor: A Brief Case Report

Affiliations
  • 1Department of Pathology, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Korea. ykpark@khmc.or.kr
  • 2Department of Otorhinolaryngology, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.

Abstract

Jugulotympanic paragangliomas (JTPs) known as glomus tumors, are neoplasms of variable invasiveness that arise from the paraganglia situated around the jugular bulb or middle ear. We now report a rare case of JTP in an 18-year-old male. Preoperative diagnoses through external auditory canal biopsy and radiologic examination both failed. Even using a frozen section, an informative finding was not obtained because mostly granulation tissue was present along with associated squeezing artifacts. On permanent histologic examination, small cell nests between many ectatic small vessels and fibrotic stroma were seen, and those cells were positive for CD56, synaptophysin and chromogranin. Because JTPs are rare and have rather different histologic findings - higher vascularity, smaller and less uniform tumor cells than other paragangliomas - they are easy to misdiagnose. However, remembering those differences may help the physician avoid missing JTPs.

Keyword

Paraganglioma, extra-adrenal; Glomus tympanicum; Glomus jugulare
Full Text Links
  • KJP
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr