Korean J Otolaryngol-Head Neck Surg.  2007 Apr;50(4):314-318.

Clinical Evaluation and Proper Antibiotics Therapy in Office Base for the Patients Who were Infected with MRSA after ESS

• Park HJ
• Oh SJ
• Jin JW
• Rho YS

Abstract

BACKGROUND AND OBJECTIVES
Methicillin resistant staphylococcus aureus (MRSA) prevalence has increased over the world during past several decades and now it has become a world wide problem. It is especially more serious in domestic situations but unfortunately, until this time, there is no report about MRSA infection treatment after endoscopic sinus surgery (ESS). The objective of our study is to evaluate clinical feature of MRSA infection and to find out what kinds of treatment is the best way to control of the MRSA infection after ESS.
SUBJECTS AND METHOD
The medical records of 58 patients who had the evidence that they were infected with MRSA after ESS were retrospectively reviewed. Samples were obtained by sinus endoscopy in the office base.
RESULTS
Those of MRSA infected only cases were 26 cases. Co-infected cases with another microorganism were 32 cases. Forty-three cases were treated with oral rifampin alone and 11 cases were treated by a combination with oral quinolone or trimethoprim-sulfimethoxazole. Four cases failed to be treated with oral antibiotic therapy.
CONCLUSION
Rifampin is the useful medication for the treatment of MRSA infected patients who had underwent ESS. Also, Rifampin is a cost effective medication compared with the glycopeptide antibiotics especially if it is used in the office base.

Keyword

Endoscopic surgical procedure; Methicillin; Antibiotics; Rifampin

MeSH Terms

Anti-Bacterial Agents*
Endoscopy
Humans
Medical Records
Methicillin
Methicillin Resistance
Methicillin-Resistant Staphylococcus aureus*
Prevalence
Retrospective Studies
Rifampin
Staphylococcus aureus
Anti-Bacterial Agents
Methicillin
Rifampin