Korean J Pediatr Gastroenterol Nutr.  2004 Sep;7(2):163-169.

Comparison between 24 hr pH Monitoring and Esophageal Scintigrapy in Children Presenting with Gastroesophageal Reflux Symptoms

Affiliations
  • 1Department of Pediatrics, College of Medicine, Hanyang University, Korea. kyjoo@hanyang.ac.kr
  • 2Department of Pediatrics, Nuclear Medicine, College of Medicine, Hanyang University, Korea.

Abstract

PURPOSE: Many diagnostic modalities have been used for diagnosis of gastroesophageal reflux disease (GERD). Feeding materials during esophageal pH monitoring may interfere the result of examination and esophageal pH monitoring can not diagnose GER in case of alkaline reflux. The purpose of our study is to evaluate whether scintigraphy can substitiute 24 hr pH monitoring in children with GERD.
METHODS
From March 2002 to June 2003, 23 patients (12 boys and 11 girls, mean age 27 months) who have been admitted to Hanyang University Hospital presented with GER symptoms (recurrent vomiting, cough, chest pain, irritability) were included in the study. Scintigraphy and 24 hr pH monitoring were performed in all patients.
RESULTS
Six out of the 23 patients (26.1%) had evidence of GER on 24 hr pH monitoring, whereas nine of 23 patients (39.2%) exhibited GER by scintigraphy. Two out of the 23 patients could not be tested because of irritability. Three (14.3%) patients had evidence of GER on both 24 hr pH monitoring and scintigraphy, three (14.3%) patients on only 24 hr pH monitoring, six (28.6%) patients on only scintigraphy, and nine (42.9%) patients had no evidence of GER on both methods. No correlation was observed between 24 hr pH monitoring and scintigraphic results by Fisher's exact test (p=0.523) or Kendal's tau (t=0.678).
CONCLUSION
The results of this study demonstrated that there was no correlation between 24 hr pH monitoring and scintigraphy. Therefore these modalities could be used as complementary tests to diagnose GERD.

Keyword

Gastroesophageal reflux (GER); Scintigraphy; Esophageal pH monitoring; Children

MeSH Terms

Chest Pain
Child*
Cough
Diagnosis
Esophageal pH Monitoring
Female
Gastroesophageal Reflux*
Humans
Hydrogen-Ion Concentration*
Radionuclide Imaging
Vomiting
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