Korean J Obstet Gynecol.  2010 Mar;53(3):287-290. 10.5468/kjog.2010.53.3.287.

Second trimester listeriosis followed by fetal death in utero (FDIU): A case report

Affiliations
  • 1Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea. jsparkmd@snu.ac.kr
  • 2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.

Abstract

Listeriosis is an infectious disease caused by Listeria monocytogenes, a gram positive, facultatively anaerobic bacterium. Listeriosis occurs primarily in newborn infants, elderly patients, immunocompromised patients and pregnant women. One third of the patients are pregnant women, and complications of this disease include miscarriage, stillbirth and preterm labor. We experienced a case of listeriosis in a singleton pregnancy at 23rd week of gestation that presented with fever, chill, lower abdominal pain, backache, and eventually resulted in fetal death in utero. Autopsy results of the stillborn baby, as well as blood and amniotic fluid culture of the mother confirmed Listeria monocytogenes infection. Proper antibiotics therapy thereafter led to clear recovery of the infected mother. We report this case with a brief review of literature.

Keyword

Listeria; Amniocentesis; Culture; Fetal death; Autopsy

MeSH Terms

Abdominal Pain
Abortion, Spontaneous
Aged
Amniocentesis
Amniotic Fluid
Anti-Bacterial Agents
Autopsy
Back Pain
Communicable Diseases
Female
Fetal Death
Fever
Humans
Immunocompromised Host
Infant, Newborn
Listeria
Listeria monocytogenes
Listeriosis
Mothers
Obstetric Labor, Premature
Pregnancy
Pregnancy Trimester, Second
Pregnant Women
Stillbirth
Anti-Bacterial Agents

Figure

  • Figure 1 The dead fetus before fixation shows disseminated whitish papules all over the surface, sparing its face and scalp.

  • Figure 2 Fetal right lung shows disseminated whitish spots on the surface.


Reference

1. Skogberg K, Syrjänen J, Jahkola M, Renkonen OV, Paavonen J, Ahonen J, et al. Clinical presentation and outcome of listeriosis in patients with and without immunosuppressive therapy. Clin Infect Dis. 1992. 14:815–821.
Article
2. Mead PS, Slutsker L, Dietz V, McCaig LF, Bresee JS, Shapiro C, et al. Food-related illness and death in the United States. Emerg Infect Dis. 1999. 5:607–625.
Article
3. Centers for Disease Control and Prevention (CDC). Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food--10 states, 2007. MMWR Morb Mortal Wkly Rep. 2008. 57:366–370.
4. Mylonakis E, Paliou M, Hohmann EL, Calderwood SB, Wing EJ. Listeriosis during pregnancy: a case series and review of 222 cases. Medicine (Baltimore). 2002. 81:260–269.
11. Chi JG. Listeriosis in a Stillborn Fetus (An Autopsy Case). Seoul J Medi. 1989. 30:181–188.
14. Linnan MJ, Mascola L, Lou XD, Goulet V, May S, Salminen C, et al. Epidemic listeriosis associated with Mexican-style cheese. N Engl J Med. 1988. 319:823–828.
Article
15. Olsen SJ, Patrick M, Hunter SB, Reddy V, Kornstein L, MacKenzie WR, et al. Multistate outbreak of Listeria monocytogenes infection linked to delicatessen turkey meat. Clin Infect Dis. 2005. 40:962–967.
16. Gottlieb SL, Newbern EC, Griffin PM, Graves LM, Hoekstra RM, Baker NL, et al. Multistate outbreak of Listeriosis linked to turkey deli meat and subsequent changes in US regulatory policy. Clin Infect Dis. 2006. 42:29–36.
Article
17. MacDonald PD, Whitwam RE, Boggs JD, MacCormack JN, Anderson KL, Reardon JW, et al. Outbreak of listeriosis among Mexican immigrants as a result of consumption of illicitly produced Mexican-style cheese. Clin Infect Dis. 2005. 40:677–682.
Article
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