Korean J Obstet Gynecol.
2009 Feb;52(2):212-219.
Clinicopathologic characteristics and prognostic factors of primary peritoneal carcinoma
- Affiliations
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- 1Department of Obstetrics & Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea. beob@kcch.re.kr
- 2Department of Obstetrics & Gynecology, National Cancer Center, Gyeonggi, Korea.
Abstract
OBJECTIVE
The objective of this study was to examine the clinicopathologic characteristics and prognostic factors of primary peritoneal carcinoma (PPC).
METHODS
Clinicopathologic variables were obtained by examining the medical records of patients with PPC who were diagnosed and treated at our institute, between January 1996 and December 2005. To find prognostic factors, the association of clinicopathologic variables with survival was evaluated by univariate and multivariate analysis.
RESULTS
All patients had advanced-stage tumors. Residual tumor was smaller than 1 cm in 12 patients and was equal or larger than 1 cm in nine patients. The response rate to adjuvant chemotherapy was 47.6%. The median progression-free survival was eight months (range 1~95) and the median overall survival was 14 months (range 1~99). In univariate analysis, stage, the response to adjuvant chemotherapy, and neoadjuvant chemotherapy were associated with survival. However, in multivariate analysis, no variables were associated with survival.
CONCLUSION
In spite of aggressive treatments, patients with PPC had poor prognosis. No prognostic factors were identified in this study.
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