Korean J Obstet Gynecol.  1999 Aug;42(8):1839-1843.

A Case of Cyclopia Associated with Trisomy 13

• Seok JH
• Chung SW
• Son SK
• Lee RR
• Lee DH
• Kang IK
• Kim IS

Abstract

Cyclopia is rare congenital craniofacial anomaly, in which the eyes are fused together and located in a single orbit. It is consistently associated with severe holoprosencephaly, which is the failure of cleavage of the prosencephalon with a deficit in the midline facial development. chromosomal study revealed 47, X( ), +13 (Patau syndrome).

Keyword

Cyclopia; Holoprosencephaly; Patau syndrome; Trisomy 13

MeSH Terms

Holoprosencephaly
Orbit
Prosencephalon
Trisomy*