Korean J Med.  2015 Feb;88(2):127-134. 10.3904/kjm.2015.88.2.127.

Treatment of Heart Failure with Reduced Ejection Fraction: Current Update

Affiliations
  • 1Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea. djchoi@snu.ac.kr
  • 2Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 3Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

Abstract

The prevalence of heart failure (HF) has been steadily increasing and it now creates an enormous social and economic burden. HF is a syndrome characterized by a high mortality rate, frequent hospitalization, a reduced quality of life, and a complex therapeutic regimen. In the last three decades, major progress in both the diagnosis and management of HF has taken place, and the pharmacologic and non-pharmacologic advances have led to a significant improvement in survival and symptoms in HF patients. After an accurate diagnosis, a proper HF management plan requires a multi-level team approach comprised of the correct combination of drug therapy, device therapy, and surgery, including heart transplantation. In this review, we focused on the pharmacologic and non-pharmacologic treatment strategies for HF with reduced ejection fraction. The goal was to develop treatment guidelines based on significant evidence derived from large clinical trials.

Keyword

Systolic heart failure; Practice guideline

MeSH Terms

Diagnosis
Drug Therapy
Heart Failure*
Heart Failure, Systolic
Heart Transplantation
Hospitalization
Humans
Mortality
Prevalence
Quality of Life
Full Text Links
  • KJM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr