Korean J Med.  2015 Nov;89(5):604-608. 10.3904/kjm.2015.89.5.604.

Acute Transverse Myelitis in a Patient with Rheumatoid Arthritis Treated with Intravenous Immunoglobulin

Affiliations
  • 1Division of Rheumatology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea. kiwonmoon@kangwon.ac.kr

Abstract

Acute transverse myelitis (ATM) is a heterogeneous syndrome characterized by acute spinal cord dysfunction resulting in paresis and sensory and autonomic impairment below the level of the lesion. The etiology of ATM includes parainfectious, paraneoplastic, drug-induced, systemic autoimmune disorders, and acquired demyelinating diseases. ATM is very rare in patients with rheumatoid arthritis (RA). A 79-year-old woman with RA, a recurring peptic ulcer, and congestive heart failure presented with acute weakness of both upper and lower extremities. She was diagnosed with ATM based on the results of laboratory and radiological tests. ATM is usually treated with high-dose glucocorticoid. However, we treated her with intravenous immunoglobulin (IVIG) considering the adverse events of high-dose glucocorticoid, and she improved. We report a case of ATM in a patient with RA successfully treated with IVIG.

Keyword

Myelitis, Transverse; Rheumatoid arthritis; Immunoglobulin

MeSH Terms

Aged
Arthritis, Rheumatoid*
Demyelinating Diseases
Female
Heart Failure
Humans
Immunoglobulins*
Immunoglobulins, Intravenous
Lower Extremity
Myelitis, Transverse*
Paresis
Peptic Ulcer
Spinal Cord
Immunoglobulins
Immunoglobulins, Intravenous
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