Korean J Med.  2013 Feb;84(2):186-195.

Proton Pump Inhibitor for Gastroesophageal Reflux Disease: Intelligent Prescription

• Jo YJ

Abstract

Gastroesophageal reflux disease (GERD) has a chronicity and its symptoms wax and wane by proton pump inhibitor (PPI) therapy. Chronic consumption of PPI in the patients with GERD is common, and we can cope with a PPI failure or refractory GERD. Therefore, we review various alternative modalities for chronic PPI treatment and an approach for refractory GERD. PPI has a potential for side effects. Many studies have been published the side effects of long-term PPI using. Mostly clinical level of evidence is weak and the absolute risk is low, however we may discuss the patients who need long-term PPI therapy about the controversial side effects, and manage those appropriately.

Keyword

Gastroesophageal reflux; Proton pump inhibitors; Safety management

MeSH Terms

Gastroesophageal Reflux
Humans
Phosphatidylethanolamines
Prescriptions
Proton Pump Inhibitors
Proton Pumps
Protons
Safety Management
Phosphatidylethanolamines
Proton Pump Inhibitors
Proton Pumps
Protons