Korean J Med.  2013 Jul;85(1):15-21.

Effects of Antiplatelet Drugs in Cardiovascular Prevention

  • 1Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. hylee612@snu.ac.kr


Hypertension and atherosclerosis are associated with a prothrombotic or hypercoagulable state, as evident by abnormalities of haemostasis, platelets and endothelial function. Therefore, in high risk hypertensive patients, use of antiplatelet agent might be beneficial in preventing thrombotic complication such as myocardial infarction and ischemic stroke. Aspirin 100 mg daily is recommended for hypertensive patients who have one of the following categories: secondary prevention +/- cardiovascular complications, primary prevention having one of risk factors such as age > 50 years + target organ damage, a 10-year CHD risk > 15%, or type II diabetes mellitus. However, it should kept in mind that aspirin treatment be initiated after stabilization of blood pressure < 150/90 mmHg.


Hypertension; Antiplatelet; Aspirin
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