Korean J Community Nutr.  2012 Apr;17(2):205-214. 10.5720/kjcn.2012.17.2.205.

Intakes of Antioxidant Nutrients and Carotenoids according to Lens Turbidity Level among Adults Visiting Cataract Clinic

Affiliations
  • 1Department of Food and Nutrition, Sungshin Women's University, Seoul, Korea. hsahn@sungshin.ac.kr
  • 2Department of Ophthalmology, Kyung Hee University Hospital at Gangdong, College of Medicine, Seoul, Korea.

Abstract

This study examined intakes of nutrients, carotenoids and polyphenols according to lens turbidity levels among adults visiting a cataract clinic. A total of 102 males and females aged 40 years or higher agreed to participate in the study, and a face-to-face survey interview was conducted to obtain information on general characteristics, health behaviors, and dietary intakes of each participant. The dietary data were collected by a food frequency questionnaire which was previously validated in a Korean population. In addition to essential nutrients, intakes of a total of 10 carotenoids and polyphenols were calculated based on the tables of food functional composition developed by National Academy of Agricultural Science. The subjects were divided into 3 groups according to turbidity levels (< 16, > or = 16 and < 25, < or = 25), and health behaviors and dietary intakes were compared among the turbidity groups. Data showed seemingly higher energy intake and lower dietary antioxidant (i.e., vitamin A, beta-carotene, lutein, zeazanthin, lycopene, cryptozanthin) intakes in the highest turbidity group. However, no statistically significant findings were found in all the comparative analysis on characteristics of health behavior and intakes of nutrients, carotenoids and polyphenols. The current study findings should be cautiously interpreted in consideration of several limitations including a cross-sectional study design, a small sample size, uneven sample size distribution across turbidity groups, and limited generalizability due to using a convenience sample. Therefore we cannot conclude that the risk of cataract is unrelated with dietary antioxidant intakes based solely on the results of this study.

Keyword

cataract; turbidity; carotenoids; antioxidants

MeSH Terms

Adult
Aged
Antioxidants
beta Carotene
Carotenoids
Cataract
Cross-Sectional Studies
Energy Intake
Female
Health Behavior
Humans
Lutein
Male
Polyphenols
Surveys and Questionnaires
Sample Size
Vitamin A
Antioxidants
Carotenoids
Lutein
Polyphenols
Vitamin A
beta Carotene

Reference

1. Ahn YJ, Lee JE, Cho NH, Shin C, Park C, Oh BS, Kim KC. Validation and calibration of semi-quantitative food frequency questionnaire-with participants of the Korean health and genome study-. Korean J Community Nutr. 2004. 9(2):173–182.
2. Bone RA, Landrum JT, Fernandez L, Tarsis SL. Analysis of the macular pigment by HPLC : retinal distribution and age study. Invest Ophthalmol Vis Sci. 1988. 29(6):843–849.
3. Brown L, Rimm EB, Seddon JM, Giovannucci EL, Chasan-Taber L, Spiegelman D, Willett WC, Hankinson SE. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr. 1999. 70(4):517–524.
4. Christen WG Jr. Antioxidants and eye disease. Am J Med. 1994. 97(3A):14S–17S.
5. Christen WG, Glynn RJ, Hennekens CH. Antioxidants and age-related eye disease; current and future perspectives. Ann Epidemiol. 1996. 6:60–66.
6. Christen WG, Liu S, Glynn RJ, Gaziano JM, Buring JE. Dietary carotenoids, vitamins and E, and risk of cataract in women: a prospective study. Arch Ophthalmol. 2008. 126(1):102–109.
7. Christen WG, Liu S, Schaumberg DA, Buring JE. Fruit and vegetable intake and the risk of cataract in women. Am J Clin Nutr. 2005. 81(6):1417–1422.
8. Chung HW, Shyn KH. An epidemiological study for relationship between risk factors and types of cataract. J Korean Ophthalmol Soc. 1995. 36(2):227–233.
9. Delcourt C, Carriere I, Delage M, Barberger-Gateau P, Schalch W. POLA Study Group. Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract : the POLA Study. Invest Ophthalmol Vis Sci. 2006. 47(6):2329–2335.
10. Dherani M, Murthy GV, Gupta Sk, Young IS, Maraini G, Camparini M, Price GM, John N, Chakravarthy U, Fletcher AE. Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian Population. Invest Ophthalmol Vis Sci. 2008. 49(8):3328–3335.
11. Fernandez MM, Afshari NA. Nutrition and the prevention of cataracts. Curr Opin Ophthalmol. 2008. 19(1):66–70.
12. Gritz DC, Srinivasan M, Smith SD, kim U, Lietman TM, Wilkins JH, Priyadharshini B, John RK, Aravind S, Prajna NV, Duraisami Thulasiraj R, Whitcher JP. The Antioxidants in prevention of cataract study : effects of antioxidant supplements on cataract progression in South India. Br J Ophthalmol. 2006. 90(7):847–851.
13. Hong SJ, Park WC, Rho SH. Epidemiology of risk factors for cataract at Chang-Nyung district, Kyung-Nam province. J Korean Ophthalmol Soc. 1998. 39(1):80–91.
14. Kanthan GL, Mitchell P, Burlutsky G, Wang JJ. Alcohol consumption and the long-term incidence of cataract and cataract surgery : the blue mountains eye study. Am J Ophthalmol. 2010. 150(3):434–440.
15. Kim JH. Cataract. Seoul: Ilchokak;18–20.
16. Kim BG, Yoo YS, Kim HK. The role of nitric oxide in the cataract development : a possible mechanism of lens opacity. J Korean Ophthalmol Soc. 2002. 43(4):757–763.
17. Kim YO, Choi HJ, Lee SY. The relationship between ophthalmic refractive errors and factors of nutrition and health. Korean J Community Nutr. 2000. 5(4):608–614.
18. Ko YS, Hong YJ, Chung HY, Kim SY, Lee YC. A study on antioxidant system in cataract patients. Korean J Nutr. 2002. 35(2):229–236.
19. Ko YS, Park JW, Lee SH, Lee YC, Hong YJ. Serum concentration of antioxidant minerals in cataract patients. J Korean Ophthalmol Soc. 2003. 44(10):2358–2363.
20. Koo JY, Kim WK, Seo JS, Son SM, Lee YS. Diet therapy principle & practice. 2007. Paju: Kyomunsa;305.
21. Korea Centers for Disease Control and Prevention. The third Korea national health and nutrition examination survey (KNHANES VI-3). 2009. Seoul: Korea Centers for Disease Control and Prevention.
22. Krishnaiah S, Vilas K, Shamanna BR, Rao GN, Thomas R, Balasubramanian D. Smoking and its association with cataract : results of the Andhra Pradesh eye disease study from India. Invest Ophthalmol Vis Sci. 2005. 46(1):58–65.
23. Risk factors of dietary intake affecting cataract. 2009. Ewha Woman University;1–3. 51–53. MS thesis.
24. Ma L, Lin XM. Effects of lutein and zeaxanthin on aspects of eye health. J Sci Food Agric. 2010. 90(1):2–12.
25. Mares-Perlman JA, Millen AE, Ficek TL, Hankinson SE. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. 2002. 132(3):518S–524S.
26. Ministry of Health & Welfare, Korea Centers for Disease Control and Prevention. 2008 National health statistics - The 4th Korea national health and nutrition examination survey, the second year (2008). 2008. Korea: Korea Centers for Disease Control and Prevention.
27. National Academy of Agricultural Science. Tables of food functional composition first edition, National academy of agricultural science. 2009. Munyoungdang: Suwon;1–349.
28. Annual statistics. National Health Insurance Corperation. 2002. cited 2003 October 18. Available from http://www.nhic.or.kr.
29. Olmedilla B, Granado F, Blanco I, Vaquero M. Lutein, but Not α-tocopherol, supplementation improves visual funtion in patients with age-related cataracts : a 2-y double-blind, placebo-controled Pilot Study. Nutrition. 2003. 19(1):21–24.
30. Park SS, Lee EH. Relations of cataract to metabolic syndrome and its components-based on the KNHANES 2005, 2007. J Korean Ophthalmic Opt Soc. 2009. 14(3):103–108.
31. Vision problems in the U.S. fourth edition. Prevent Blindness America. 2008. cited 2011 June 28. Available from http://www.preventblindness.org.
32. Rautiainen S, Lindblad BE, Morgenstern R, Wolk A. Vitamin C supplements and the risk of age-related cataract : a population-based prospective cohort study in women. Am J Clin Nutr. 2010. 91(2):487–493.
33. Rosales P, Marcos S. Pentacam scheimpflug quantitative imaging of the crystalline lens and intraocular lens. J Refract Surg. 2009. 25(5):421–428.
34. Selvi R, Angayarkanni N, Biswas J, Ramakrishan S. Total antioxidant capacity in Eales' disease, uveitis & cataract. Indian J Med Res. 2011. 134(1):83–90.
35. Shyn KH, Kim JC, Kim WS, Ahn BH, Lee JH, Ro SH, Song JK, Lee YH. An epidemiological study of the risk factors contributing to the senile cataractogenesis by the Korea Cooperative Cataract Epidemiology Study Group(KCCESG). J Korean Ophthalmol Soc. 1992. 33(2):127–134.
36. Tan AG, Mitchell P, Flood VM, Burlutsky G, Rochtchina E, Cumming RG, Wang JJ. Antioxidant nutrient intake and the long-term incidence of age-related cataract : the Blue Mountains Eye Study. Am J Clin Nutr. 2008. 87(6):1899–1905.
37. The Korean Nutrition Society. Dietary reference intakes for Koreans. 2005. Seoul: Korean Nutrition Society.
38. Thylefors B, Negrel AD, Pararajasegaram R, Dadzie KY. Golbal data on bilndness. Bull WHO. 1995. 73:115–121.
39. Valero MP, Fletcher AE, De Stavola BL, Vioque J, Alepuz VC. Vitamin C is associated with reduced risk of cataract in a mediterranean population. J Nutr. 2002. 132(6):1299–1306.
40. Vu HT, Robman L, Hodge A, Mccarty CA, Taylor HR. Lutein and zeaxanthin and the risk of cataract : the Melbourne Visual Impairment Project. Invest Ophthalmol Vis Sci. 2006. 47(9):3783–3786.
41. West S, Munoz B, Schein OD, Vitale S, Maquire M, Taylor HR, Bressler NM. Cigarette smoking and risk for progression of nuclear opacities. Arch Ophthalmol. 1995. 113(11):1377–1380.
42. West SK, Valmadrid CT. Epidemiology of risk factors for age related cataract. Surv Ophthalmol. 1995. 39(4):323–334.
43. Williams PT. Prospective epidemiological cohort study of reduced risk for incident cataract with vigorous physical activity and cardiorespiratory fitness during a 7-year follow-up. Invest Ophthalmol Vis Sci. 2009. 50(1):95–100.
44. Zigler JS Jr, Jernigan HM, Reddy VN. The effects of "oxygen radicals" generated in the medium in lenses in organ culture; inhibition of damage by chelated iron. Arch Biochem Biophys. 1985. 241(1):163–172.
Full Text Links
  • KJCN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr