Ann Dermatol.  2009 Aug;21(3):311-314. 10.5021/ad.2009.21.3.311.

A Case of Eczema Herpeticum with Hailey-Hailey Disease

Affiliations
  • 1Department of Dermatology, Soonchunhyang University College of Medicine, Seoul, Korea. dermsung@schca.ac.kr

Abstract

Eczema herpeticum is the dissemination of herpes simplex virus in the setting of a preexisting skin disease. Hailey- Hailey disease [familial benign chronic pemphigus] is a blistering dermatosis that is inherited as an autosomal dominant trait and it usually presents itself around the third or fourth decades. Coexistence of eczema herpeticum and Hailey-Hailey disease is an infrequent occurrence. Four such cases have been reported in the English and German medical literature. We report here on an unusual case of eczema herpeticum that coexisted with Hailey-Hailey disease in a 47 years old man and we review the relevant literatures.

Keyword

Eczema herpeticum; Hailey-Hailey disease

MeSH Terms

Blister
Eczema
Kaposi Varicelliform Eruption
Methylmethacrylates
Pemphigus, Benign Familial
Polystyrenes
Simplexvirus
Skin Diseases
Methylmethacrylates
Polystyrenes

Figure

  • Fig. 1 Multiple umbilicated vesicles on the chin.

  • Fig. 2 Erythematous scaly plaque with maceration of the inguinal area (A), the nape of the neck (B) and the axilla (C).

  • Fig. 3 Intraepidermal clefts suprabasally in the epidermis and the characteristic acantholysis with the appearance of a "dilapidated brick wall" (H&E stain, ×100).


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