Ann Dermatol.  2014 Aug;26(4):539-540. 10.5021/ad.2014.26.4.539.

A Case of Multiple Eruptive Dermatofibromas in a Healthy Adult

Affiliations
  • 1Department of Dermatology, School of Medicine, Kangwon National University, Chuncheon, Korea.
  • 2Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea. dermakkh@naver.com

Abstract

No abstract available.


MeSH Terms

Adult*
Histiocytoma, Benign Fibrous*
Humans

Figure

  • Fig. 1 (A) Multiple brownish, dome-shaped nodules that were 5~10 mm in diameter on the trunk and legs. (B) A bean-sized, brownish, firm nodule on the right thigh.

  • Fig. 2 (A) Excision biopsy of 1 papule on the right thigh showed a relatively well- demarcated dermal nodule overlaid by hyperplastic epidermis with basal hyperpigmentation (H&E, ×20). (B) Proliferation of spindle-shaped fibrohistiocytic cells arranged in a storiform pattern in the dermis (H&E, ×200). (C) Immunohistochemical analysis revealed that many of the lesion cells were positive for factor XIIIa (×200).


Reference

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5. Nestle FO, Nickoloff BJ, Burg G. Dermatofibroma: an abortive immunoreactive process mediated by dermal dendritic cells? Dermatology. 1995; 190:265–268.
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