Ann Dermatol.  2013 Nov;25(4):512-514. 10.5021/ad.2013.25.4.512.

Cockarde (Target-Like Lesion) Seborrheic Keratosis: An Unusual Clinical Pattern

• Yoon NY
• Kim BK
• Hong SP
• Jeon SY
• Ahn SK

• KMID: 2265079
• DOI: http://doi.org/10.5021/ad.2013.25.4.512

Abstract

No abstract available.

MeSH Terms

Keratosis, Seborrheic*

Figure

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  Fig. 1 Targetoid seborrheic keratosis. Central black plaque surrounded by a brownish patch. A subsequent elliptical biopsy was performed containing the inner round plaque and a part of the surrounding patch (Asterisk: round black inner plaque. Black and white arrow: light brown arcuate patch surrounding inner plaque).

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  Fig. 2 Histopathologic characteristics of seborrheic keratosis (clonal type). (A, B) Histopathological examination revealed generalized hyperkeratosis, acanthosis, and a proliferation of sharply demarcated intraepithelial nests of large pale cells in the epidermis of the central lesion. The adjacent epidermis in the biopsy lied on a straight line. (C) Histopathological examination revealed intraepithelial nests of large cells and melanophages in the upper dermis (A: H&E, ×40; B: H&E, ×100; C: H&E, ×200) (Asterisk: histopathologic findings of round black inner plaque. Black and white arrow: histopathologic findings of the surrounding light brown arcuate patch).

Reference

1. Hafner C, Vogt T. Seborrheic keratosis. J Dtsch Dermatol Ges. 2008; 6:664–677.

2. Wolf R, Lipozencic J. Shape and configuration of skin lesions: targetoid lesions. Clin Dermatol. 2011; 29:504–508.

3. Guzzo C, Johnson B, Honig P. Cockarde nevus: a case report and review of the literature. Pediatr Dermatol. 1988; 5:250–253.

4. Hughey LC. Approach to the hospitalized patient with targetoid lesions. Dermatol Ther. 2011; 24:196–206.

5. Bryant J. Conservative clinical diagnoses in seborrheic keratosis. Arch Dermatol. 1998; 134:752–753.