Korean J Med.  2011 Nov;81(5):663-666.

Intravesical Cidofovir in the Treatment of Hemorrhagic Cystitis after Unrelated Cord Blood Transplantation

Affiliations
  • 1Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. sychong@cha.ac.kr

Abstract

Hemorrhagic cystitis is a common complication in hematopoietic stem cell transplant recipients. We report a case of hemorrhagic cystitis after unrelated cord blood transplantation associated with adenovirus infection. Despite hydration, hematuria and large clots persisted. We instilled cidofovir into the bladder, which resulted in clearance of the adenovirus and significant clinical improvement. Our case emphasizes the effectiveness of intravesical cidofovir treatment for viral hemorrhagic cystitis.

Keyword

Adenovirus; Cystitis; Cidofovir; Cord blood stem cell transplantation

MeSH Terms

Adenoviridae
Adenoviridae Infections
Cord Blood Stem Cell Transplantation
Cystitis
Cytosine
Fetal Blood
Hematopoietic Stem Cells
Hematuria
Organophosphonates
Transplants
Urinary Bladder
Cytosine
Organophosphonates
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