Korean J Med.  2011 Sep;81(3):403-407.

Case of Synchronous Primary Gastric Diffuse Large B-Cell Lymphoma and Hepatocellular Carcinoma

  • 1Department of Internal Medicine, Ajou University School of Medicine, Suwon, Korea. seonghyunmd@naver.com


Primary gastric lymphoma is relatively rare in the context of gastric malignancies. Synchronous primary gastric lymphoma and hepatocellular carcinoma (HCC) are even rarer. We report a case of synchronous primary gastric lymphoma and HCC in a 46-year-old man that appeared to be associated with hepatitis B virus infection. Pathologic examination and immunohistochemical analysis of gastric and liver specimens showed diffuse large B-cell lymphoma and HCC, respectively. The patient was initially treated for primary gastric lymphoma with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) chemotherapy. During the chemotherapy interval, he was treated for HCC by transarterial chemoembolization (TACE) and laparoscopy-assisted left hemihepatectomy.


Non-Hodgkin lymphoma; Hepatocellular carcinoma
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