Korean J Med.  2010 May;78(5):654-659.

A case of sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Korea. healthyra@chosun.ac.kr

Abstract

Sarcoidosis is a multisystemic granulomatous disorder that commonly involves the lungs, skin, and eyes. The coexistence of sarcoidosis with a kidney disorder and pulmonary hemorrhage is extremely rare. Hypercalciuria and hypercalcemia are the most common manifestations of renal involvement, although granulomatous interstitial nephritis, glomerular disease, and obstructive uropathy also occur in sarcoidosis. Acute tubular necrosis associated with acute renal failure generally shows early remission. In Korea, no cases of sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage have been reported. Here, we describe the case of a 65-year-old man with stage 3 sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage. The patient was treated with steroid and hydroxychloroquine for approximately 1 month. Most of his symptoms improved gradually, and he has been symptom-free since then.

Keyword

Sarcoidosis; Acute tubular necrosis; Pulmonary hemorrhage

MeSH Terms

Acute Kidney Injury
Aged
Eye
Hemorrhage
Humans
Hydroxychloroquine
Hypercalcemia
Hypercalciuria
Kidney
Korea
Lung
Necrosis
Nephritis, Interstitial
Sarcoidosis
Skin
Hydroxychloroquine
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