Korean J Med.  2010 Dec;79(6):710-713.

A case of syndrome of inappropriate secretion of antidiuretic hormone associated with paroxetine

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea. dr52916@catholic.ac.kr

Abstract

Paroxetine is a well-known selective serotonin reuptake inhibitor, and has been reported to be advantageous for chronic pain control. Paroxetine is increasingly used for various types of chronic pain because of its safety; however, hyponatremia, or syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with paroxetine, has been reported. This complication is relatively rare, but some patients have presented with severe neurological symptoms. Here, we report the first case of SIADH associated with paroxetine in Korea.

Keyword

Paroxetine; Syndrome of inappropriate secretion of antidiuretic hormone

MeSH Terms

Chronic Pain
Humans
Hyponatremia
Inappropriate ADH Syndrome
Korea
Paroxetine
Serotonin
Paroxetine
Serotonin
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