Korean J Med.  2008 Dec;75(6):689-693.

A case of hyperphosphatemia and acute renal failure following the administration of solin(R) (oral sodium phosphate)

Affiliations
  • 1Department of Internal Medicine, Yongdong Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea. Hask1951@yumc.yonsei.ac.kr

Abstract

Solin(R) (oral sodium phosphate) is a commonly used osmotic laxative solution that has replaced polyethylene glycol in bowel preparation for colonoscopy as it has equal or greater efficacy and patient compliance. However, its use has been associated with several cases of acute renal failure and electrolyte imbalance, especially hyperphosphatemia and hypocalcemia. Those at higher risk of complications are patients who are older and have intestinal obstruction, inflammatory bowel disease, renal failure, or congestive heart failure. We report the case of a 61-year-old woman presenting with paresthesia in both hands after using Solin(R) for bowel preparation for colonoscopy. The patient had hypocalcemia and hyperphosphatemia combined with acute renal failure. She recovered from the renal failure and electrolyte imbalance with intravenous hydration and treatment with phosphate-binding agents.

Keyword

Oral sodium phosphate; Acute renal failure; Hyperphosphatemia

MeSH Terms

Acute Kidney Injury
Colonoscopy
Female
Hand
Heart Failure
Humans
Hyperphosphatemia
Hypocalcemia
Inflammatory Bowel Diseases
Intestinal Obstruction
Middle Aged
Paresthesia
Patient Compliance
Polyethylene Glycols
Renal Insufficiency
Sodium
Polyethylene Glycols
Sodium
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