Korean J Med.  2009 Oct;77(4):488-492.

A case of ischemic gastric necrosis after submucosal epinephrine injection

Affiliations
  • 1Institute for Digestive Research, Digestive Disease Center, Soonchunhyang University Medical College, Seoul, Korea. drjslee@dreamwiz.com

Abstract

Ischemic gastric necrosis is rare because of the abundant anastomotic supply to the stomach, and it is usually associated with surgery and disruption of the major vessels. Although the injection of epinephrine is safe and effective for non.variceal bleeding, it may cause tissue necrosis. Six cases of ischemic gastric necrosis after submucosal epinephrine injection have been reported. We describe a case of ischemic gastric necrosis after submucosal epinephrine injection in a 61.year.old woman with hypertension and angina pectoris treated with antihypertensives and aspirin. We should exercise caution when injecting epinephrine submucosally in a patient with atherosclerotic risk factors such as old age, hypertension, diabetes mellitus, or angina pectoris due to a possible risk of ischemic gastric necrosis.

Keyword

Epinephrine; Ischemia; Injection; Necrosis; Stomach

MeSH Terms

Angina Pectoris
Antihypertensive Agents
Aspirin
Diabetes Mellitus
Epinephrine
Female
Hemorrhage
Humans
Hypertension
Ischemia
Necrosis
Risk Factors
Stomach
Antihypertensive Agents
Aspirin
Epinephrine
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