Korean J Med.  2009 Aug;77(Suppl 1):S16-S20.

A case of deep, wide drug-induced esophageal ulcer

Affiliations
  • 1Department of Internal Medicine, Sun General Hospital, Daejeon, Korea. hyounmokang@hanmail.net

Abstract

There are many possible causes of esophageal ulcer, including reflux esophagitis, the ingestion of foreign bodies or caustic agents, radiation exposure, viral infections, tuberculosis, Candida infection, Bechet's disease, and esophageal cancer. Patients with drug-induced esophagitis typically have a history of ingesting medication with little or no fluid immediately before going to bed. Here, we present the case of a 31-year-old man complaining of dysphagia and odynophagia for 4 days. The patient reported taking oral medication for acute sinusitis 12 days prior. Endoscopic examination revealed a large, deep esophageal ulcer consistent with esophageal cancer or cytomegalovirus esophagitis. The exam also revealed several esophageal erosions resembling herpes simplex virus esophagitis. However, based on the patient's history and subsequent histologic findings, drug-induced esophagitis was diagnosed and the patient was successfully treated with a proton pump inhibitor. Lesions showed improvement upon follow-up endoscopy 1 month later.

Keyword

Drug-induced esophagitis

MeSH Terms

Adult
Candida
Cytomegalovirus
Deglutition Disorders
Eating
Endoscopy
Esophageal Neoplasms
Esophagitis
Esophagitis, Peptic
Follow-Up Studies
Foreign Bodies
Humans
Methylmethacrylates
Polystyrenes
Proton Pumps
Simplexvirus
Sinusitis
Tuberculosis
Ulcer
Methylmethacrylates
Polystyrenes
Proton Pumps
Full Text Links
  • KJM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr