Korean J Cerebrovasc Surg.  2011 Sep;13(3):206-214.

Outcome of Decompressive Hemicraniectomy for Treating Malignant Cerebral Infarction

Affiliations
  • 1Department of Neurosurgery, Jeju National University Institute of Medical Science, Jeju, Korea. nschangsub@jejunu.ac.kr
  • 2Department of Emergency Medicine, Jeju National University Institute of Medical Science, Jeju, Korea.
  • 3Department of Neurology, Jeju National University Institute of Medical Science, Jeju, Korea.
  • 4Jeju National University School of Medicine, Jeju National University Institute of Medical Science, Jeju, Korea.

Abstract

OBJECTIVE: This study is aimed to describe our experience with performing hemicraniectomy for treating patients with malignant cerebral infarction. This study also aimed at describing the difference between our experience and that of the published articles.
METHODS
Ten patients who had anterior circulation territory cerebral infarction underwent decompressive hemicraniectomy for treating their life threatening brain swelling between August 2004 and October 2007. We retrospectively analyzed the patients' medical records and radiological films and we described the patients' clinical and radiological details. The outcomes were measured according to the case fatality rate at 2 weeks and the modified Rankin scale (mRS) at 9 months. We compared our institution's outcomes with the pooled analysis result of three randomized controlled trials (DESTINY, DECIMAL, HAMLET trial).
RESULTS
Nine men and one woman were included in this study. Their mean age was 61.5 +/- 11.9 years, and the mean National Institute of Health Stroke Scale (NIHSS) score on admission was 17.3 +/- 6.0. Five patients died within 2 weeks after operation. Four patients had a mRS of 5 and one had a mRS of 4 at 9 months. Our series included elder patients (mean difference : 9.9~18.3 years) who had a low NIHSS score on admission (mean difference : -4.8~-6.8) as compared to that of the pooled analysis group. Our series revealed a higher proportion of an unfavorable outcome (mRS > or = 4) compared to that of the pooled analysis results (p=0.01). No patient in our series would have been eligible, according to the inclusion criteria, for inclusion in the pooled analysis studies.
CONCLUSION
We think that the higher proportion of an unfavorable outcome in our series was a consequence of the elder age of our patients.

Keyword

Cerebral infarction; Hemicraniectomy; Elder age; Outcome
Full Text Links
  • KJCS
Share
  • Twitter
  • Facebook
Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr