Korean J Med.
2006 Dec;71(6):683-687.
A case of autoimmune insulin syndrome
- Affiliations
-
- 1Department of Internal Medicine, Korea University College of Medicine, Ansan, Korea. nhkim@kumc.or.kr
Abstract
- Autoimmune insulin syndrome is characterized by a combination of fasting hypoglycemia, high total serum insulin concentrations, and the presence of autoantibodies to the native human insulin in serum. A healthy 69-year-old man developed spontaneous hypoglycemia after being given some medications for the common cold. His laboratory finding shows endogenous hyperinsulinism. Therefore, an insulinoma was suspected but the imaging study shows no mass lesion in the pancreas and the anti-insulin antibody titer was high(>100U/mL). He had no specific medication history except for a treatment of a current upper respiratory infection (URI). Among the URI medication, it was found that N-acetylcysteine contains a sulfhydryl group and could induce autoimmunization. The patient was treated with corticosteroid for 3 months. His anti-insulin antibody titer had decreased to normal level and has not shown any hypoglycemic episodes for more than one and a half years. We present this case with a review of relevant literature.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Anti-tuberculosis Treatment-Induced Insulin Autoimmune Syndrome
- Insulin Autoimmune Syndrome with Diabetic Ketoacidosis
- A case of insulin autoimmune syndrome
- A case of insulin autoimmune syndrome related to alpha-lipoic acid
- A Case of Primary Insulin Autoimmune Syndrome in a Patient Suspected of Having an Insulinoma
