Korean J Med.  2006 Dec;71(6):662-667.

A case of gastrointestinal stromal tumor of the stomach showing exophytic growth

Affiliations
  • 1Department of Internal Medicine, St. Carollo Hospital, SunCheon, Korea. rapael64@hanmail.net
  • 2Department of Pathology, St. Carollo Hospital, SunCheon, Korea.
  • 3Department of Surgery, St. Carollo Hospital, SunCheon, Korea.

Abstract

Gastroinstestinal stromal tumors (GISTs) are defined as a group of KIT (CD117) positive mesenchymal tumors. Approximately 70% of those tumors are found in the stomach followed in order by the small bowel, colon and rectum, esophagus. The common clinical presentation of GISTs varies according to the size and location of the tumors, ranging from massive gastrointestinal bleeding to vague abdominal pain. We detected a GIST of the stomach incidentally during chest-computed tomography examination of a 68-year-old-woman. Esophagogastroduodenoscopy showed an 8 cm sized protruded lesion with normal mucosal covering on the posterior wall of the gastric body, and endoscopic ultrasonography showed a cystic mass originating in the fourth layer of the stomach. The patient was treated with a subtotal gastrectomy. Immunohistochemical studies on the surgical resection specimen showed CD117(+) and CD34(+). The final diagnosis was a GIST of the stomach showing exophytic growth.

Keyword

Stomach; Gastrointestinal stromal tumor; Exophytic growth

MeSH Terms

Abdominal Pain
Colon
Diagnosis
Endoscopy, Digestive System
Endosonography
Esophagus
Gastrectomy
Gastrointestinal Stromal Tumors*
Hemorrhage
Humans
Rectum
Stomach*
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