Korean J Nephrol.  1997 Jun;16(2):365-368.

Mixed or Combined IgA Nephropathy and Membranous Glomerulonephritis

Affiliations
  • 1Department of Pathology, Wonju College of Medicine Yonsei University, Korea.
  • 2Department of Pathology, School of Medicine Ajou University, Korea.
  • 3Department of Internal Medicine, School of Medicine Ajou University, Korea.

Abstract

We report a rare case of primary glomerular disease with both features of IgA nephropathy and membranous glomerulonephritis in a 45 year-old, HBsAg negative man with nephrotic syndrome. Histologically, glomeruli showed mesangial expansion, proliferation of mesangial cells, and diffuse thickening of capillary walls. Direct immunofluorescence demonstrated granular IgG and C3 deposits along the capillary walls and IgA deposits in mesangiums. Granular subepithelial and mesangial depoists were observed by electron microscopy.

Keyword

IgA nephropathy; Membranous glomerulonephritis

MeSH Terms

Capillaries
Fluorescent Antibody Technique, Direct
Glomerulonephritis, IGA*
Glomerulonephritis, Membranous*
Hepatitis B Surface Antigens
Humans
Immunoglobulin A*
Immunoglobulin G
Mesangial Cells
Microscopy, Electron
Middle Aged
Nephrotic Syndrome
Hepatitis B Surface Antigens
Immunoglobulin A
Immunoglobulin G
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