Korean J Nephrol.  1997 Dec;16(4):828-835.

A Case of Multiple Myeloma of Kappa Light Chain Type Associated with Gastric Amyloidosis and Acute Renal Failure and Pathologic Fracture Due to Femur Plasmacytoma

  • 1Department of Nephrology, Ajou University School of Medicine, Suwon, Korea.
  • 2Department of Pathology, Ajou University School of Medicine, Suwon, Korea.


Primary amyloidosis has been reported to develop in 6 to 15% of patients with multiple myeloma and especially in 20 to 24% of patients with light chain myeloma. Although deposition of amyloid in the gastric mucosa is common in primary systemic amyloidosis(AL), gastric amyloidosis in AL type is rarely symptomatic. Also, pathologic fracture of the femur secondary to plasmacytoma is quite rare for the first manifestation of multiple myeloma. A case of gastric amyloidosis associated with gastric outlet obstruction and femur plasmacytoma in multiple myeloma is reported with review of literatures.


Myeloma kidney; Plasmacytoma; Multiple myeloma; Gastric amyloidosis
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