Korean J Nephrol.  2006 Mar;25(2):343-347.

A Case of Acute Renal Failure Caused by Ingestion of Glacial Acetic Acid

• Lee YM
• Jung SW
• Ju HJ
• Shim H
• Shin JH
• Baek SH
• Seo GS
• Ahn SH
• Song JH

Abstract

Acetic acid is a colorless liquid with a pungent vinegar-like order. Glacial acetic acid is 99% acetic acid. Acetic acid may lead to different effect on the damaged organ. Acetic acid ingestion is most common and results in pharyngeal, esophageal and GI burns, bleeding and volume depletion. Systemic effect include hemolysis, hepatic dysfunction, hypotension, renal failure and disseminated intravascular coagulation after ingestion of 90-100% acetic acid. Acute renal failure in acetic acid poisoning is rare and the mechanism of acute renal failure remains unclear. But tubular toxic effect of myoglobin or hemoglobin and direct action of acetic acid are suggested as the mechanism. Because of the acute renal failure may be fatal, the immediate treatment of hemolysis, substitution of blood and clotting factor and hemodialysis lead to improvement in general condition and renal function.

Keyword

Acute renal failure; Glacial acetic acid

MeSH Terms

Acetic Acid*
Acute Kidney Injury*
Burns
Disseminated Intravascular Coagulation
Eating*
Hemolysis
Hemorrhage
Hypotension
Myoglobin
Poisoning
Renal Dialysis
Renal Insufficiency
Acetic Acid
Myoglobin