Korean J Nephrol.  2007 Nov;26(6):744-747.

A Case of Rhabdomyolysis and Acute Renal Failure Associated with Primary Hypothyroidism

Affiliations
  • 1Department of Internal Medicine, Kwandong University College of Medicine, Goyang, Korea. drjoy@kd.ac.kr

Abstract

Hypothyroidism is a clinical state which results from decreased production of thyroid hormone, and its symptoms are various including lack of energy, dryness of skin and hair, dyspnea, bradycardia, hypotension, body weight gain, and constipation. Muscle disorders due to hypothyroidism may include myalgia, muscle weakness, stiffness, delayed tendon reflex, abnormality of electromyography, changes of muscle tissues and increased muscle enzymes. Hypothyroid myopathy manifests as a mild form of myopathy rather than an acute rhabdomyolysis, that is a very rare complication of hypothyroid myopathy and that can cause acute renal failure. We report a case of primary hypothyroidism presented with rhabdomyolysis and acute renal failure. A 50-year-old male referred to our hospital for evaluation and management of generalized edema, muscle weakness, fatigue and myalgia. He had acute rhabdomyolysis and progressed to acute renal failure due to newly developed primary hypothyroidism. After hormone replacement therapy with levothyroxine, the patients renal function and muscular symptom completely recovered.

Keyword

Acute renal failure; Hypothyroidism; Rhabdomyolysis; Myopathy

MeSH Terms

Acute Kidney Injury*
Body Weight
Bradycardia
Constipation
Dyspnea
Edema
Electromyography
Fatigue
Hair
Hormone Replacement Therapy
Humans
Hypotension
Hypothyroidism*
Male
Middle Aged
Muscle Weakness
Muscular Diseases
Myalgia
Reflex, Stretch
Rhabdomyolysis*
Skin
Thyroid Gland
Thyroxine
Thyroxine
Full Text Links
  • KJN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr