Korean J Nephrol.  2008 Mar;27(2):264-269.

A Case of Primary Hepatic Angiosarcoma after Renal Transplantation

Affiliations
  • 1Department of Internal Medicine, Gachon University of Medicine and Science, Incheon, Korea. jcyjs@dreamwiz.com
  • 2Department of Pathology, Gachon University of Medicine and Science, Incheon, Korea.
  • 3Department of Surgery, Gachon University of Medicine and Science, Incheon, Korea.

Abstract

Malignancy is one of the important complications after renal transplantation, and decreases both patient survival and graft survival. Hepatic angiosarcoma is the most common sarcoma in liver, but a rare malignant tumor which occupies about 2% of all hepatic malignancies. We report a case of primary hepatic angiosarcoma after renal transplantation, the first case of post-transplantation angiosarcoma in Korea. A 27-year old man had received a living related renal transplantation. He was admitted due to clinical manifestations of liver cirrhosis such as ascites, spontaneous bacterial peritonitis, and varix bleeding at 8 months after transplantation. Whole liver was infiltrated with angiosarcoma; therefore, he was managed only by supportive care. Considering the poor prognosis of hepatic angiosarcoma, both careful screening of malignancy before transplantation and periodic surveillance of malignancy after transplantation are essential.

Keyword

Hemangiosarcoma; Kidney transplantation; Neoplasms

MeSH Terms

Ascites
Graft Survival
Hemangiosarcoma
Hemorrhage
Humans
Kidney Transplantation
Korea
Liver
Liver Cirrhosis
Mass Screening
Peritonitis
Prognosis
Sarcoma
Transplants
Varicose Veins
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