Korean J Nephrol.  2008 Mar;27(2):251-255.

A Case of End-Stage Renal Disease (ESRD) from Reflux Nephropathy in a patient with Situs Inversus and Duplicated Ureter

• Kim YK
• Kim MO
• Choi SY
• Choi HJ
• Han HY
• Huh WS
• Oh HY
• Kim SJ

Abstract

Situs inversus is a rare congenital anomaly that occurs in adults at the rate of 1:5,000-1:10,000. In the total form, the thoracic organs, as well as the abdominal organs, are completely reversed in a "mirror image" of their normal arrangements. Ureteral duplication is the most common ureteral anomaly founded incidentally. However, there is a higher incidence of duplication in cases of urinary tract infection, and it may be associated with upper urinary tract stasis, obstruction, or reflux. But ureteral duplication has no relation to situs inversus. Vesicoureteral reflux (VUR) is the most common disorder usually detected during radiologic evaluation of children with urinary tract infection. Complications such as renal scarring, reflux nephropathy, chronic renal failure and hypertension are well known in patients with VUR. Reflux nephropathy is responsible for about 10% of all cases of treated ESRD and is the most common case of ESRD in children. Thus, if VUR exists, early diagnosis and intensive treatment is necessary. Herein, we present a case of reflux nephropathy related ESRD in a 41-year-old woman with total situs inversus and duplicated ureter.

Keyword

Situs inversus; Vesico-ureteral reflux; End stage renal disease (ESRD)

MeSH Terms

Adult
Child
Cicatrix
Early Diagnosis
Female
Humans
Hypertension
Incidence
Kidney Failure, Chronic
Situs Inversus
Ureter
Urinary Tract
Urinary Tract Infections
Vesico-Ureteral Reflux